FILM: H.P. Mendoza, the creator of Colma: The Musical, brings us another acclaimed musical, Fruit Fly, which has been described as "flashy, trashy, and brazenly fun," about a performance artist who moves to San Francisco and discovers she might be a "fag hag."

4:45, 7 and 9:30 p.m. // Castro Theatre (429 Castro St) // $7.50-10

SCIENCE: The latest edition of the hugely popular Nerd Nite SF #4: Old SF, Synthetic Biology, Sexual Mishaps will teach attendees about old San Francisco, including a neighborhood called "Beer Town," the wonders of bioengineering, and the wild world of sexual mishaps.

7:30 to 11 p.m. // Rickshaw Stop (155 Fell St) // $8

HISTORY: The California Historical Society presents the monthly California Nights, back by popular demand, which will continue through November. "Connect, learn, and discuss the future of the great state of California, all while listening to California-themed music and enjoying complementary refreshments."

5 to 8 p.m. // California Historical Society (678 Mission St) // free