BENEFIT: Kentucky Fried Woman will perform at Hotties 4 H0m0 Health Care, tonight's benefit for Lyon-Martin Health Clinic, which is trying to raise $250k in order to stay open. Also on the bill are Drew Montana, Brock Cocker, Lyric Styles, and Dottie Lux, along with DJ Booty Klap (Party Hole!!!) and DJs HLAWS & Jxn James (Transfat). There's also a raffle featuring lots of great sex toy prizes.

7 to 10 p.m. // El Rio (3158 Mission St) // $5-20, 21+

COMEDY: Hosts Kumail Nanjiani (The Colbert Report) and Jonah Ray (the Nerdist podcast) bring The Meltdown, a weekly live show at L.A.'s Meltdown Comics, to SF Sketchfest, featuring Doug Benson (The Benson Interruption), Rich Fulcher (The Mighty Boosh), Thomas Lennon (Reno 911!), Greg Proops (Whose Line Is It Anyway?) and April Richardson (Breakfast with the Smiths).

8 p.m. // Cobb’s Comedy Club (915 Columbus Ave) // $30

MUSIC: The Bay Area Rainbow Symphony (BARS) presents A Tenor In Winter: Benefit Concert & World Premiere, showcasing music for tenor strings, and winds by Arthur Bliss, Bohuslav Martinu, Monteverdi, Schubert, and a world-premiere by David Conte, and featuring tenor Brian Thorsett. All ticket sales and proceeds will benefit Larkin Street Youth Services.

5 p.m. // Calvary Presbyterian Church (2515 Fillmore St) // pay what you can