MUSIC: Local faves, The Fresh & Onlys, will rock the Great American tonight with their signature sound, which takes "a little from here and a little from there, sometimes from fifties rock, or from elastic garage or from the immaculate pop of the Byrds," along with co-headliners Tamaryn and guests Wax Idols. (8 p.m., Great American Music Hall, 859 O'Farrell Street)

STREET FAIR: Lower 24th Street Merchants & Neighbors Association presents First Friday on 24th, featuring food tasting, art, music, children's activities and performers including fire jugglers, a pre-teen rock band, samba dancers, a puppet show, SF Lowrider Car Clubs, and more. (6 to 10 p.m., 24th St. from Mission St. to Potrero Ave)

ART: Friday Nights at the de Young and the Bay Guardian presents Get Sketchy with Picasso, which bids "adios" to the de Young's Picasso exhibit, presenting SF Improv Fest and the Freeze, live sketching, Spanish guitar, and more. (6 to 8:45 p.m., de Young Museum, 50 Hagiwara Tea Garden Drive)